There is an 18th century fort, Fort Prinzenstein, built in 1784 by the Danes at Keta. This fort played a significant role in the slave trade involving Europeans in West Africa, the Caribbean and southern USA.
The Portuguese founded Castle "Sao Jorge and Mina" in 1482 to protect the gold-rich lands discovered in 1471. The castle was completed according to its original plan in 1486 and the town was raised to the status of a "city".
Anomabu became the focus of intense European trade rivalry in the 17th and 18th centuries, partly because of its easy access to a rich hinterland and partly because the local Anomabu were themselves powerful and astute traders.
History has it that, in 1631, a renegade employee of the Dutch West Indian Company called Arent Groote, acting on behalf of the English Company of Adventurers Trading to Guynney and Binney, signed an agreement with the Chief of Cormantin by which a hill site near the village was ceded to the English company.
In 1503, according to historical narration by the Portuguese Diego de Alvarenga, a Portuguese missionary converted and baptized the paramount chief of the Efutu Kingdom on the Mina coast together with 300 of his subjects.